The Project Runway pair have led the series through 16 seasons with ratings success.
While Bravo signed up for a new season of the title in May, the duo will not return to it and neither will designer Zac Posen, who has been with the show since season 11.
Details are scarce on the upcoming show, but Amazon has said in a statement that the series will be a fresh take in the reality space and will appeal to a global audience “who are entertained by competition, storytelling and authenticity.”
Additionally, Amazon Fashion will create a shoppable experience for viewers of the title.
Jennifer Salke, head of Amazon Studios, said: “Heidi Klum completely changed the television landscape by developing a competitive reality fashion series that was unproven and different from what was popular on-air. The show became wildly successful, and in turn Klum and Tim Gunn have become an iconic pop culture duo.
“Their drive to deliver fashionably entertaining, engaging and trendsetting content speaks for itself, and we believe their next iteration in this space will find an even larger audience on our global Prime Video runway.”
Klum added: “After 16 incredible seasons, I am saying ‘Auf Wiedersehen’ to Project Runway, a show that I was honored to host and help create. I am incredibly proud of the show, and it will always have a special place in my heart. I am so appreciative of the dedicated fans, and most of all, I am grateful that we could shine a light on creativity and help launch so many talented designers’ careers.
“I’m most excited that my journey with my dear friend and colleague, Tim Gunn, is far from over. We will be partnering with Amazon for a new show, and we’re excited for everyone to see what we’re designing next!”